T cell antigen discovery via Signaling and Antigen presenting Bifunctional Receptors

CD8+ T cells recognize and eliminate tumors in an antigen-specific manner. Despite progress in characterizing the antitumor T cell repertoire and function, identifying their target antigens remains a challenge. Here, we describe the use of chimeric receptors called Signaling and Antigen-presenting B...

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Detalles Bibliográficos
Autores principales: Joglekar, Alok V., Leonard, Michael T., Jeppson, John D., Swift, Margaret, Li, Guideng, Wong, Stephanie, Peng, Songming, Zaretsky, Jesse M., Heath, James R., Ribas, Antoni, Bethune, Michael T., Baltimore, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755906/
https://www.ncbi.nlm.nih.gov/pubmed/30700902
http://dx.doi.org/10.1038/s41592-018-0304-8

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