H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas

Uterine leiomyomas or fibroids (UFs) are benign tumors characterized by hyperplastic smooth muscle cells and excessive deposition of extracellular matrix (ECM). Afflicting ~80% of women, and symptomatic in 25%, UFs bring tremendous suffering and are an economic burden worldwide; they cause severe pa...

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Detalles Bibliográficos
Autores principales: Cao, Tiefeng, Jiang, Ying, Wang, Zhangsheng, Zhang, Na, Al-Hendy, Ayman, Mamillapalli, Ramanaiah, Kallen, Amanda N., Kodaman, Pinar, Taylor, Hugh S., Li, Da, Huang, Yingqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755985/
https://www.ncbi.nlm.nih.gov/pubmed/31089260
http://dx.doi.org/10.1038/s41388-019-0808-4

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