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Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer

Ovarian cancer is a heterogeneous malignancy that poses tremendous clinical challenge. Based on unsupervised classification of whole-genome gene expression profiles, four molecular subtypes of ovarian cancer were recently identified. However, single-driver molecular events specific to these subtypes...

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Detalles Bibliográficos
Autores principales: Zhao, Linjie, Wang, Wei, Xu, Lian, Yi, Tao, Zhao, Xia, Wei, Yuquan, Vermeulen, Louis, Goel, Ajay, Zhou, Shengtao, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755993/
https://www.ncbi.nlm.nih.gov/pubmed/30478449
http://dx.doi.org/10.1038/s41388-018-0577-5