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Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS

One of the hallmarks of B lymphoid malignancies is a B cell clone characterized by a unique footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic marker for clonality assessment. The EuroClonality/BIOMED-2 assay is currently the gold standard for analyzing IG heavy...

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Detalles Bibliográficos
Autores principales:	Scheijen, Blanca, Meijers, Ruud W. J., Rijntjes, Jos, van der Klift, Michèle Y., Möbs, Markus, Steinhilber, Julia, Reigl, Tomas, van den Brand, Michiel, Kotrová, Michaela, Ritter, Julia-Marie, Catherwood, Mark A., Stamatopoulos, Kostas, Brüggemann, Monika, Davi, Frédéric, Darzentas, Nikos, Pott, Christiane, Fend, Falko, Hummel, Michael, Langerak, Anton W., Groenen, Patricia J. T. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756030/ https://www.ncbi.nlm.nih.gov/pubmed/31197258 http://dx.doi.org/10.1038/s41375-019-0508-7

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