An actionable axis linking NFATc2 to EZH2 controls the EMT-like program of melanoma cells

Discovery of new actionable targets and functional networks in melanoma is an urgent need as only a fraction of metastatic patients achieves durable clinical benefit by targeted therapy or immunotherapy approaches. Here we show that NFATc2 expression is associated with an EMT-like transcriptional pr...

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Detalles Bibliográficos
Autores principales: Perotti, Valentina, Baldassari, Paola, Molla, Alessandra, Nicolini, Gabriella, Bersani, Ilaria, Grazia, Giulia, Benigni, Fabio, Maurichi, Andrea, Santinami, Mario, Anichini, Andrea, Mortarini, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756060/
https://www.ncbi.nlm.nih.gov/pubmed/30710146
http://dx.doi.org/10.1038/s41388-019-0729-2

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