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High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse

Cancer is a major cause of death in children worldwide, with B-lineage cell acute lymphoblastic leukemia (B-ALL) being the most frequent childhood malignancy. Relapse, treatment failure and organ infiltration worsen the prognosis, warranting a better understanding of the implicated mechanisms. Corta...

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Detalles Bibliográficos
Autores principales: Velázquez-Avila, Martha, Balandrán, Juan Carlos, Ramírez-Ramírez, Dalia, Velázquez-Avila, Mirella, Sandoval, Antonio, Felipe-López, Alfonso, Nava, Porfirio, Alvarado-Moreno, José Antonio, Dozal, David, Prieto-Chávez, Jessica L., Schaks, Matthias, Rottner, Klemens, Dorantes-Acosta, Elisa, López-Martínez, Briceida, Schnoor, Michael, Pelayo, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756064/
https://www.ncbi.nlm.nih.gov/pubmed/30573781
http://dx.doi.org/10.1038/s41375-018-0333-4