Uncoupling the widespread occurrence of anti-NMDAR1 autoantibodies from neuropsychiatric disease in a novel autoimmune model

Autoantibodies of the IgG class against N-methyl-D-aspartate-receptor subunit-NR1 (NMDAR1-AB) were considered pathognomonic for anti-NMDAR encephalitis. This view has been challenged by the age-dependent seroprevalence (up to >20%) of functional NMDAR1-AB of all immunoglobulin classes found in &g...

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Detalles Bibliográficos
Autores principales: Pan, Hong, Oliveira, Bárbara, Saher, Gesine, Dere, Ekrem, Tapken, Daniel, Mitjans, Marina, Seidel, Jan, Wesolowski, Janina, Wakhloo, Debia, Klein-Schmidt, Christina, Ronnenberg, Anja, Schwabe, Kerstin, Trippe, Ralf, Mätz-Rensing, Kerstin, Berghoff, Stefan, Al-Krinawe, Yazeed, Martens, Henrik, Begemann, Martin, Stöcker, Winfried, Kaup, Franz-Josef, Mischke, Reinhard, Boretius, Susann, Nave, Klaus-Armin, Krauss, Joachim K., Hollmann, Michael, Lühder, Fred, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756099/
https://www.ncbi.nlm.nih.gov/pubmed/29426955
http://dx.doi.org/10.1038/s41380-017-0011-3

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