Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair

The melanocytic lineage, which is prominently exposed to ultraviolet radiation (UVR) and radiation-independent oxidative damage, requires specific DNA-damage response mechanisms to maintain genomic and transcriptional homeostasis. The coordinate lineage-specific regulation of intricately intertwined...

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Detalles Bibliográficos
Autores principales: Seoane, Marcos, Buhs, Sophia, Iglesias, Pablo, Strauss, Julia, Puller, Ann-Christin, Müller, Jürgen, Gerull, Helwe, Feldhaus, Susanne, Alawi, Malik, Brandner, Johanna M., Eggert, Dennis, Du, Jinyan, Thomale, Jürgen, Wild, Peter J., Zimmermann, Martin, Sternsdorf, Thomas, Schumacher, Udo, Nollau, Peter, Fisher, David E., Horstmann, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756118/
https://www.ncbi.nlm.nih.gov/pubmed/30651597
http://dx.doi.org/10.1038/s41388-018-0661-x

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