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NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells

We previously showed that NADPH oxidase organizer 1 (Noxo1), a component of NADPH oxidase 1 (NOX1), is a TNF-α-induced tumor-promoting factor in gastric tumorigenesis. However, the mechanism of NOX1-induced reactive oxygen species (ROS) signaling for the gastric tumorigenesis has not been understood...

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Detalles Bibliográficos
Autores principales:	Echizen, Kanae, Horiuchi, Keigo, Aoki, Yayoi, Yamada, Yoichi, Minamoto, Toshinari, Oshima, Hiroko, Oshima, Masanobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756228/ https://www.ncbi.nlm.nih.gov/pubmed/30700829 http://dx.doi.org/10.1038/s41388-019-0702-0

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