Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis

Invadopodia are cell protrusions that mediate cancer cell extravasation but the microenvironmental cues and signaling factors that induce invadopodia formation during extravasation remain unclear. Using intravital imaging and loss of function experiments, we determined invadopodia contain receptors...

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Detalles Bibliográficos
Autores principales: Williams, Karla C., Cepeda, Mario A., Javed, Sumreen, Searle, Karlee, Parkins, Katie M., Makela, Ashley V., Hamilton, Amanda M., Soukhtehzari, Sepideh, Kim, Yohan, Tuck, Alan B., Ronald, John A., Foster, Paula J., Chambers, Ann F., Leong, Hon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756237/
https://www.ncbi.nlm.nih.gov/pubmed/30651600
http://dx.doi.org/10.1038/s41388-018-0667-4

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