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Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention
The immunosuppressive agent mycophenolate is used extensively in kidney transplantation, yet dosing strategy applied varies markedly from fixed dosing (“one-dose-fits-all”), to mycophenolic acid (MPA) trough concentration monitoring, to dose optimization to an MPA exposure target (as area under the...
Autores principales: | Metz, David K., Holford, Nick, Kausman, Joshua Y., Walker, Amanda, Cranswick, Noel, Staatz, Christine E., Barraclough, Katherine A., Ierino, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756255/ https://www.ncbi.nlm.nih.gov/pubmed/31584924 http://dx.doi.org/10.1097/TP.0000000000002762 |
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