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Robust methods in Mendelian randomization via penalization of heterogeneous causal estimates
Methods have been developed for Mendelian randomization that can obtain consistent causal estimates under weaker assumptions than the standard instrumental variable assumptions. The median-based estimator and MR-Egger are examples of such methods. However, these methods can be sensitive to genetic v...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756542/ https://www.ncbi.nlm.nih.gov/pubmed/31545794 http://dx.doi.org/10.1371/journal.pone.0222362 |