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The outcome of the HCC patients underwent ALPPS: Retrospective study

The complete resection offers the best long-term survival for advanced hepatocellular carcinoma patients. ALPPS as a choice of resection, how is its outcome compared to one-stage resection, liver transplantation and TACE? This retrospective study included 20 ALPPS patients. To minimize the effect of...

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Autores principales: Peng, Chihan, Li, Chuan, Liu, Chang, Wen, Tianfu, Yang, Jiayin, Li, Bo, Yan, Lvnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756621/
https://www.ncbi.nlm.nih.gov/pubmed/31567959
http://dx.doi.org/10.1097/MD.0000000000017182
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author Peng, Chihan
Li, Chuan
Liu, Chang
Wen, Tianfu
Yang, Jiayin
Li, Bo
Yan, Lvnan
author_facet Peng, Chihan
Li, Chuan
Liu, Chang
Wen, Tianfu
Yang, Jiayin
Li, Bo
Yan, Lvnan
author_sort Peng, Chihan
collection PubMed
description The complete resection offers the best long-term survival for advanced hepatocellular carcinoma patients. ALPPS as a choice of resection, how is its outcome compared to one-stage resection, liver transplantation and TACE? This retrospective study included 20 ALPPS patients. To minimize the effect of confounding influences of measured covariates, PSM was performed. The overall survival (OS), morbidity, mortality and the increasing rate, KGR were analyzed. The OS in ALPPS group is 27.4 (±3.8 months) moths and the TACE group is 13.5(±1.2 months) (P < .001), LT group is 41.3 (±3.2 months) (P = .048), Resection group is 31.8 (±2.6 months) (P = .368). And the medium increasing volume is 209.5 cm(3) (±61.5 cm(3)) with the increasing ratio 52.4% (+26.9%). The ALPPS is a feasible treatment for HCC patients and it provides a better long-term survival than TACE and it is similar to Resection, less than LT.
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spelling pubmed-67566212019-10-07 The outcome of the HCC patients underwent ALPPS: Retrospective study Peng, Chihan Li, Chuan Liu, Chang Wen, Tianfu Yang, Jiayin Li, Bo Yan, Lvnan Medicine (Baltimore) 4500 The complete resection offers the best long-term survival for advanced hepatocellular carcinoma patients. ALPPS as a choice of resection, how is its outcome compared to one-stage resection, liver transplantation and TACE? This retrospective study included 20 ALPPS patients. To minimize the effect of confounding influences of measured covariates, PSM was performed. The overall survival (OS), morbidity, mortality and the increasing rate, KGR were analyzed. The OS in ALPPS group is 27.4 (±3.8 months) moths and the TACE group is 13.5(±1.2 months) (P < .001), LT group is 41.3 (±3.2 months) (P = .048), Resection group is 31.8 (±2.6 months) (P = .368). And the medium increasing volume is 209.5 cm(3) (±61.5 cm(3)) with the increasing ratio 52.4% (+26.9%). The ALPPS is a feasible treatment for HCC patients and it provides a better long-term survival than TACE and it is similar to Resection, less than LT. Wolters Kluwer Health 2019-09-20 /pmc/articles/PMC6756621/ /pubmed/31567959 http://dx.doi.org/10.1097/MD.0000000000017182 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 4500
Peng, Chihan
Li, Chuan
Liu, Chang
Wen, Tianfu
Yang, Jiayin
Li, Bo
Yan, Lvnan
The outcome of the HCC patients underwent ALPPS: Retrospective study
title The outcome of the HCC patients underwent ALPPS: Retrospective study
title_full The outcome of the HCC patients underwent ALPPS: Retrospective study
title_fullStr The outcome of the HCC patients underwent ALPPS: Retrospective study
title_full_unstemmed The outcome of the HCC patients underwent ALPPS: Retrospective study
title_short The outcome of the HCC patients underwent ALPPS: Retrospective study
title_sort outcome of the hcc patients underwent alpps: retrospective study
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756621/
https://www.ncbi.nlm.nih.gov/pubmed/31567959
http://dx.doi.org/10.1097/MD.0000000000017182
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