The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor

Aggressive therapies for patients with metastatic Wilms tumor (WT) with subsequent severe late effects warrant the search for novel therapies. The role of focal adhesion kinase (FAK), a non-receptor tyrosine kinase important in pediatric solid tumor development and progression, has not been examined...

Descripción completa

Detalles Bibliográficos
Autores principales: Aye, Jamie M., Stafman, Laura L., Williams, Adele P., Garner, Evan F., Stewart, Jerry E., Anderson, Joshua C., Mruthyunjayappa, Smitha, Waldrop, Mary G., Goolsby, Caroline D., Markert, Hooper R., Quinn, Colin, Marayati, Raoud, Mroczek-Musulman, Elizabeth, Willey, Christopher D., Yoon, Karina J., Whelan, Kimberly F., Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756857/
https://www.ncbi.nlm.nih.gov/pubmed/31565187
http://dx.doi.org/10.18632/oncotarget.27165

Ejemplares similares

Ejemplares similares