Kindlin-3 in platelets and myeloid cells differentially regulates deep vein thrombosis in mice

Platelets and myeloid cells cooperate to promote deep vein thrombosis (DVT). Here we evaluated the role of kindlin-3, a key integrin activator in these cells, in regulating stenosis-induced DVT in mice. DVT was significantly suppressed in mice that express a kindlin-3 mutant defective for integrin b...

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Detalles Bibliográficos
Autores principales: Yan, Yanyan, Yang, Hongqin, Hu, Xiao, Zhang, Zeping, Ge, Shushu, Xu, Zhen, Gao, Juan, Liu, Junling, White, Gilbert C., Ma, Yan-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756892/
https://www.ncbi.nlm.nih.gov/pubmed/31477636
http://dx.doi.org/10.18632/aging.102229

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