The activation of cardiac dSir2-related pathways mediates physical exercise resistance to heart aging in old Drosophila

Cardiac aging is majorly characterized by increased diastolic dysfunction, lipid accumulation, oxidative stress, and contractility debility. The Sir2/Sirt1 gene overexpression delays cell aging and reduces obesity and oxidative stress. Exercise improves heart function and delays heart aging. However...

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Detalles Bibliográficos
Autores principales: Wen, Deng-Tai, Zheng, Lan, Li, Jin-Xiu, Lu, Kai, Hou, Wen-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756900/
https://www.ncbi.nlm.nih.gov/pubmed/31503544
http://dx.doi.org/10.18632/aging.102261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756900/
https://www.ncbi.nlm.nih.gov/pubmed/31503544
http://dx.doi.org/10.18632/aging.102261

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