Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer’s disease

Toll-like receptor-2 (TLR2), a member of the TLR family, plays an important role in the initiation and regulation of immune/inflammation response, which is a critical mechanism underlying Alzheimer’s disease (AD). To clarify the role of TLR2 in the pathological process of AD, in the present study, T...

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Detalles Bibliográficos
Autores principales: Zhou, Chao, Sun, Xiaoyu, Hu, Yuting, Song, Jiaxing, Dong, Shuyu, Kong, Delian, Wang, Yuqiao, Hua, Xiaodong, Han, Jingjing, Zhou, Yan, Jin, Guoliang, Yang, Xinxin, Shi, Hongjuan, Zhang, Zuohui, Hua, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756907/
https://www.ncbi.nlm.nih.gov/pubmed/31509519
http://dx.doi.org/10.18632/aging.102260

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