Human γδ T‐cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

BACKGROUND: Although γδ T cells comprise up to 10% of human peripheral blood T cells, questions remain regarding their role in disease states and T‐cell receptor (TCR) clonal expansions. We dissected anti‐viral functions of human γδ T cells towards influenza viruses and defined influenza‐reactive γδ...

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Detalles Bibliográficos
Autores principales: Sant, Sneha, Jenkins, Misty R, Dash, Pradyot, Watson, Katherine A, Wang, Zhongfang, Pizzolla, Angela, Koutsakos, Marios, Nguyen, Thi HO, Lappas, Martha, Crowe, Jane, Loudovaris, Tom, Mannering, Stuart I, Westall, Glen P, Kotsimbos, Tom C, Cheng, Allen C, Wakim, Linda, Doherty, Peter C, Thomas, Paul G, Loh, Liyen, Kedzierska, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756999/
https://www.ncbi.nlm.nih.gov/pubmed/31559018
http://dx.doi.org/10.1002/cti2.1079

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