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Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP

Munc18-1 and Munc13-1 orchestrate assembly of the SNARE complex formed by syntaxin-1, SNAP-25 and synaptobrevin, allowing exquisite regulation of neurotransmitter release. Non-regulated neurotransmitter release might be prevented by αSNAP, which inhibits exocytosis and SNARE-dependent liposome fusio...

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Detalles Bibliográficos
Autores principales:	Stepien, Karolina P., Prinslow, Eric A., Rizo, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757032/ https://www.ncbi.nlm.nih.gov/pubmed/31548544 http://dx.doi.org/10.1038/s41467-019-12188-4

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