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Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation
Stable isotope-resolved metabolomics (SIRM) provides information regarding the relative activity of numerous metabolic pathways and the contribution of nutrients to specific metabolite pools; however, SIRM experiments can be difficult to execute, and data interpretation is challenging. Furthermore,...
Autores principales: | Lorkiewicz, Pawel K., Gibb, Andrew A., Rood, Benjamin R., He, Liqing, Zheng, Yuting, Clem, Brian F., Zhang, Xiang, Hill, Bradford G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757038/ https://www.ncbi.nlm.nih.gov/pubmed/31548575 http://dx.doi.org/10.1038/s41598-019-50183-3 |
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