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Mutation profiling of cancer drivers in Brazilian colorectal cancer

The molecular basis of colorectal cancer (CRC) can guide patient prognosis and therapy. In Brazil, knowledge on the CRC mutation landscape is limited. Here, we investigated the mutation profile of 150 cancer-related genes by next-generation sequencing and associated with microsatellite instability (...

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Detalles Bibliográficos
Autores principales: dos Santos, Wellington, Sobanski, Thais, de Carvalho, Ana Carolina, Evangelista, Adriane Feijó, Matsushita, Marcus, Berardinelli, Gustavo Nóriz, de Oliveira, Marco Antonio, Reis, Rui Manuel, Guimarães, Denise Peixoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757044/
https://www.ncbi.nlm.nih.gov/pubmed/31548566
http://dx.doi.org/10.1038/s41598-019-49611-1