Cargando…

Mutation profiling of cancer drivers in Brazilian colorectal cancer

The molecular basis of colorectal cancer (CRC) can guide patient prognosis and therapy. In Brazil, knowledge on the CRC mutation landscape is limited. Here, we investigated the mutation profile of 150 cancer-related genes by next-generation sequencing and associated with microsatellite instability (...

Descripción completa

Detalles Bibliográficos
Autores principales:	dos Santos, Wellington, Sobanski, Thais, de Carvalho, Ana Carolina, Evangelista, Adriane Feijó, Matsushita, Marcus, Berardinelli, Gustavo Nóriz, de Oliveira, Marco Antonio, Reis, Rui Manuel, Guimarães, Denise Peixoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757044/ https://www.ncbi.nlm.nih.gov/pubmed/31548566 http://dx.doi.org/10.1038/s41598-019-49611-1

Ejemplares similares

Pyknon-Containing Transcripts Are Downregulated in Colorectal Cancer Tumors, and Loss of PYK44 Is Associated With Worse Patient Outcome
por: Evangelista, Adriane Feijó, et al.
Publicado: (2020)

Microbiota Profile and Impact of Fusobacterium nucleatum in Colorectal Cancer Patients of Barretos Cancer Hospital
por: de Carvalho, Ana Carolina, et al.
Publicado: (2019)

Role of Genetic Ancestry in 1,002 Brazilian Colorectal Cancer Patients From Barretos Cancer Hospital
por: Durães, Ronilson Oliveira, et al.
Publicado: (2020)

Profile of esophageal squamous cell carcinoma mutations in Brazilian patients
por: Munari, Fernanda Franco, et al.
Publicado: (2021)

Genomic profile of two Brazilian choroid plexus tumors by whole-exome sequencing
por: Garcia, Felipe Antonio de Oliveira, et al.
Publicado: (2023)

A 4-Gene Signature Associated With Recurrence in Low- and Intermediate-Risk Endometrial Cancer
por: de Andrade, Diocésio Alves Pinto, et al.
Publicado: (2021)

Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients
por: Berardinelli, Gustavo Noriz, et al.
Publicado: (2018)

Somatic targeted mutation profiling of colorectal cancer precursor lesions
por: dos Santos, Wellington, et al.
Publicado: (2022)

Combined SEPT9 and BMP3 methylation in plasma for colorectal cancer early detection and screening in a Brazilian population
por: Lima, Adhara Brandão, et al.
Publicado: (2023)

Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer
por: Datorre, José Guilherme, et al.
Publicado: (2022)

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure
por: Vicente, Anna Luiza Silva Almeida, et al.
Publicado: (2022)

ERBB2 exon 20 insertions are rare in Brazilian non‐small cell lung cancer
por: de Oliveira Cavagna, Rodrigo, et al.
Publicado: (2022)

A computational approach for the discovery of significant cancer genes by weighted mutation and asymmetric spreading strength in networks
por: Cutigi, Jorge Francisco, et al.
Publicado: (2021)

Establishment, molecular and biological characterization of HCB-514: a novel human cervical cancer cell line
por: Rosa, Marcela Nunes, et al.
Publicado: (2019)

Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients’ survival
por: Moreno, Daniel Antunes, et al.
Publicado: (2022)

Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations
por: Leal, Letícia Ferro, et al.
Publicado: (2019)

Genetic alterations detected by comparative genomic hybridization in BRCAX breast and ovarian cancers of Brazilian population
por: Felicio, Paula Silva, et al.
Publicado: (2018)

Simultaneous analysis of ALK, RET, and ROS1 gene fusions by NanoString in Brazilian lung adenocarcinoma patients
por: Novaes, Lázaro Antonio Campanha, et al.
Publicado: (2021)

Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma
por: de Carvalho, Ana Carolina, et al.
Publicado: (2015)

Erratum: Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma
por: de Carvalho, Ana Carolina, et al.
Publicado: (2015)

Mutational Profile of Driver Genes in Brazilian Melanomas
por: Vicente, Anna Luiza S.A., et al.
Publicado: (2019)

Lack of microsatellite instability in gastrointestinal stromal tumors
por: Campanella, Nathália C., et al.
Publicado: (2017)

Molecular characterization of breast cancer cell lines by clinical immunohistochemical markers
por: Mota, André de Lima, et al.
Publicado: (2017)

New insights on familial colorectal cancer type X syndrome
por: Garcia, Felipe Antonio de Oliveira, et al.
Publicado: (2022)

INACTIVE BEHAVIOR IN ADOLESCENT STUDENTS OF THE BRAZILIAN WESTERN AMAZON
por: Farias, Edson dos Santos, et al.
Publicado: (2019)

Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian Patients
por: Fernandes, Flávia Gonçalves, et al.
Publicado: (2021)

Uber use after alcohol consumption among car/motorcycle drivers in ten Brazilian capitals
por: de Aquino, Érika Carvalho, et al.
Publicado: (2023)

Recommendations for the Screening of Breast Cancer of the Brazilian College of Radiology and Diagnostic Imaging, Brazilian Society of Mastology and Brazilian Federation of Gynecology and Obstetrics Association
por: Urban, Linei Augusta Brolini Delle, et al.
Publicado: (2023)

Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis
por: Proença, Marcela Alcântara, et al.
Publicado: (2018)

Prevalence of Benign Diseases Mimicking Lung Cancer: Experience from a University Hospital of Southern Brazil
por: Homrich, Gustavo Köhler, et al.
Publicado: (2015)

Identification of MicroRNA Expression Profiles Related to the Aggressiveness of Salivary Gland Adenoid Cystic Carcinomas
por: Zanon, Maicon Fernando, et al.
Publicado: (2023)

Recommendations for breast cancer screening in Brazil, from the Brazilian College of Radiology and Diagnostic Imaging, the Brazilian Society of Mastology, and the Brazilian Federation of Gynecology and Obstetrics Associations
por: Urban, Linei Augusta Brolini Delle, et al.
Publicado: (2023)

MiR-21 as prognostic biomarker in head and neck squamous cell carcinoma patients undergoing an organ preservation protocol
por: Arantes, Lidia Maria Rebolho Batista, et al.
Publicado: (2016)

Safety and health of professional drivers who drive on Brazilian highways
por: Narciso, Fernanda Veruska, et al.
Publicado: (2017)

Cryptococcosis: Identification of Risk Areas in the Brazilian Amazon
por: dos Reis, Danielle Saraiva Tuma, et al.
Publicado: (2022)

Impact of screening on cervical cancer incidence and mortality in a Northern Brazilian city
por: Formigosa, Lucrecia Aline Cabral, et al.
Publicado: (2022)

COVID-19 and Assisted Reproduction: A Point of View on the Brazilian Scenario
por: Carvalho, Bruno Ramalho de, et al.
Publicado: (2020)

Association between religiousness and blood donation among Brazilian postgraduate students from health-related areas
por: Zangiacomi Martinez, Edson, et al.
Publicado: (2014)

Hepatitis C virus infection in Brazilian long-distance truck drivers
por: Freitas, Nara R, et al.
Publicado: (2010)

Analysis of the effects of the age-period-birth cohort on cervical cancer mortality in the Brazilian Northeast
por: Meira, Karina Cardoso, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o4v94d6mj0emc0oe8bnbna4os8