Model-based clustering for identifying disease-associated SNPs in case-control genome-wide association studies

Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing adjustment is over-conservative and lack of power in many GWAS...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yan, Xing, Li, Su, Jessica, Zhang, Xuekui, Qiu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757104/
https://www.ncbi.nlm.nih.gov/pubmed/31548641
http://dx.doi.org/10.1038/s41598-019-50229-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757104/
https://www.ncbi.nlm.nih.gov/pubmed/31548641
http://dx.doi.org/10.1038/s41598-019-50229-6

Ejemplares similares