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Model-based clustering for identifying disease-associated SNPs in case-control genome-wide association studies
Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing adjustment is over-conservative and lack of power in many GWAS...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757104/ https://www.ncbi.nlm.nih.gov/pubmed/31548641 http://dx.doi.org/10.1038/s41598-019-50229-6 |