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Prokaryotic soluble overexpression and purification of oncostatin M using a fusion approach and genetically engineered E. coli strains
Human Oncostatin M (OSM), initially discovered as a tumour inhibitory factor secreted from U-937 cells, is a gp130 (IL-6/LIF) cytokine family member that exhibits pleiotropic effects in inflammation, haematopoiesis, skeletal tissue alteration, liver regeneration, cardiovascular and metabolic disease...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757106/ https://www.ncbi.nlm.nih.gov/pubmed/31548569 http://dx.doi.org/10.1038/s41598-019-50110-6 |