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Prokaryotic soluble overexpression and purification of oncostatin M using a fusion approach and genetically engineered E. coli strains

Human Oncostatin M (OSM), initially discovered as a tumour inhibitory factor secreted from U-937 cells, is a gp130 (IL-6/LIF) cytokine family member that exhibits pleiotropic effects in inflammation, haematopoiesis, skeletal tissue alteration, liver regeneration, cardiovascular and metabolic disease...

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Detalles Bibliográficos
Autores principales:	Nguyen, Minh Tan, Prima, Musharrat Jahan, Song, Jung-A., Kim, Julee, Do, Bich Hang, Yoo, Jiwon, Park, Sangsu, Jang, Jaepyeong, Lee, Sunju, Lee, Eunyoung, Novais, Michelle de Paula, Seo, Hyeon-Beom, Lee, Seon-yeong, Cho, Mi-La, Kim, Chong Jai, Jang, Yeon Jin, Choe, Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757106/ https://www.ncbi.nlm.nih.gov/pubmed/31548569 http://dx.doi.org/10.1038/s41598-019-50110-6

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