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Absence of Entourage: Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ(9)-THC at Human CB(1) and CB(2) Receptors

Introduction: Compounds present in Cannabis sativa such as phytocannabinoids and terpenoids may act in concert to elicit therapeutic effects. Cannabinoids such as Δ(9)-tetrahydrocannabinol (Δ(9)-THC) directly activate cannabinoid receptor 1 (CB(1)) and cannabinoid receptor 2 (CB(2)); however, it is...

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Detalles Bibliográficos
Autores principales: Santiago, Marina, Sachdev, Shivani, Arnold, Jonathon C., McGregor, Iain S., Connor, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757242/
https://www.ncbi.nlm.nih.gov/pubmed/31559333
http://dx.doi.org/10.1089/can.2019.0016