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Gallbladder Polyps Are Associated with Proximal Colon Polyps
BACKGROUND: The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. METHODS: Patients who received general health checkup from January to Dec...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757279/ https://www.ncbi.nlm.nih.gov/pubmed/31611916 http://dx.doi.org/10.1155/2019/9832482 |
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author | Lee, Kuan-Chieh Jeng, Wen-Juei Hsu, Chen-Ming Kuo, Chia-Jung Su, Ming-Yao Chiu, Cheng-Tang |
author_facet | Lee, Kuan-Chieh Jeng, Wen-Juei Hsu, Chen-Ming Kuo, Chia-Jung Su, Ming-Yao Chiu, Cheng-Tang |
author_sort | Lee, Kuan-Chieh |
collection | PubMed |
description | BACKGROUND: The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. METHODS: Patients who received general health checkup from January to December 2008 were included and subgrouped into three groups by polyp location: proximal, distal, and whole colon. GB disease and other known risk factors for colon cancer were compared and analyzed. Different types of polyps at different locations were further investigated. RESULTS: Of a total of 3136 patients (1776 men and 1360 women; mean age, 49.3 years) who had colon polyps, 212 (6.8%) had GB stone and 512 (16.3%) had GB polyps. Patients in the proximal colon polyp group had higher rates of GB polyps and stones. GB polyps were independently associated with proximal colon polyps, including both hyperplastic polyps (odds ratio, 1.523; P = 0.034) and adenomatous polyps (odds ratio, 1.351; P = 0.048). No relationship between GB polyps and distal or any colon polyps was observed. Irrespective of the polyp location (i.e., proximal, distal, or any part of the colon), GB stone did not show any association with colon polyp. CONCLUSIONS: We suggested that GB polyps are associated with proximal colon polyps. Colonoscopy may be a more effective strategy for screening proximal precancerous lesions among patients with GB polyps. The association between GB disease and colon polyps demands further prospective investigation. |
format | Online Article Text |
id | pubmed-6757279 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-67572792019-10-14 Gallbladder Polyps Are Associated with Proximal Colon Polyps Lee, Kuan-Chieh Jeng, Wen-Juei Hsu, Chen-Ming Kuo, Chia-Jung Su, Ming-Yao Chiu, Cheng-Tang Gastroenterol Res Pract Research Article BACKGROUND: The association between gallbladder (GB) disease and colorectal precancerous lesions remains elusive. This study sought to explore the association between GB disease and colorectal neoplasms at different locations. METHODS: Patients who received general health checkup from January to December 2008 were included and subgrouped into three groups by polyp location: proximal, distal, and whole colon. GB disease and other known risk factors for colon cancer were compared and analyzed. Different types of polyps at different locations were further investigated. RESULTS: Of a total of 3136 patients (1776 men and 1360 women; mean age, 49.3 years) who had colon polyps, 212 (6.8%) had GB stone and 512 (16.3%) had GB polyps. Patients in the proximal colon polyp group had higher rates of GB polyps and stones. GB polyps were independently associated with proximal colon polyps, including both hyperplastic polyps (odds ratio, 1.523; P = 0.034) and adenomatous polyps (odds ratio, 1.351; P = 0.048). No relationship between GB polyps and distal or any colon polyps was observed. Irrespective of the polyp location (i.e., proximal, distal, or any part of the colon), GB stone did not show any association with colon polyp. CONCLUSIONS: We suggested that GB polyps are associated with proximal colon polyps. Colonoscopy may be a more effective strategy for screening proximal precancerous lesions among patients with GB polyps. The association between GB disease and colon polyps demands further prospective investigation. Hindawi 2019-09-12 /pmc/articles/PMC6757279/ /pubmed/31611916 http://dx.doi.org/10.1155/2019/9832482 Text en Copyright © 2019 Kuan-Chieh Lee et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lee, Kuan-Chieh Jeng, Wen-Juei Hsu, Chen-Ming Kuo, Chia-Jung Su, Ming-Yao Chiu, Cheng-Tang Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title_full | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title_fullStr | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title_full_unstemmed | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title_short | Gallbladder Polyps Are Associated with Proximal Colon Polyps |
title_sort | gallbladder polyps are associated with proximal colon polyps |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757279/ https://www.ncbi.nlm.nih.gov/pubmed/31611916 http://dx.doi.org/10.1155/2019/9832482 |
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