Protective Effects of Oridonin on Acute Liver Injury via Impeding Posttranslational Modifications of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) in the Toll-Like Receptor 4 (TLR4) Signaling Pathway

OBJECTIVE: Recent researches have demonstrated that inflammation-related diseases are effectively regulated by posttranslational modifications (PTMs) including phosphorylation and acetylation. Our previous study found a new acetyltransferase inhibitor, oridonin, which had a protective effect on acut...

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Detalles Bibliográficos
Autores principales: Shi, Min, Deng, Yilin, Yu, Heguo, Xu, Ling, Shi, Cuicui, Chen, Jiong, Li, Guangming, Du, Yiqi, Wang, Yu-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757283/
https://www.ncbi.nlm.nih.gov/pubmed/31611735
http://dx.doi.org/10.1155/2019/7634761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757283/
https://www.ncbi.nlm.nih.gov/pubmed/31611735
http://dx.doi.org/10.1155/2019/7634761

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