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Downregulated miR-21 mediates matrine-induced apoptosis via the PTEN/Akt signaling pathway in FTC-133 human follicular thyroid cancer cells

Matrine is an alkaloid extracted from the leguminous plant Sophora flavescens. Matrine has clinical effects in the treatment of tumors, including those in lung cancer, nasopharyngeal cancer and liver cancer. However, the effect of matrine on follicular thyroid cancer has not been reported. The aim o...

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Detalles Bibliográficos
Autores principales: Li, Quanliang, Zhang, Shuya, Wang, Mingyu, Dong, Shouguang, Wang, Yan, Liu, Song, Lu, Tiancheng, Fu, Yuqin, Wang, Xiuran, Chen, Guihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757298/
https://www.ncbi.nlm.nih.gov/pubmed/31579406
http://dx.doi.org/10.3892/ol.2019.10693