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A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients

BACKGROUND: The hypoxic tumor microenvironment accelerates the invasion and migration of colorectal cancer (CRC) cells. The aim of this study was to develop and validate a hypoxia gene signature for predicting the outcome in stage I/II CRC patients that have limited therapeutic options. METHODS: The...

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Detalles Bibliográficos
Autores principales:	Zou, Yi-feng, Rong, Yu-ming, Tan, Ying-xin, Xiao, Jian, Yu, Zhao-liang, Chen, Yu-feng, Ke, Jia, Li, Cheng-hang, Chen, Xi, Wu, Xiao-jian, Lan, Ping, Lin, Xu-tao, Gao, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757395/ https://www.ncbi.nlm.nih.gov/pubmed/31572060 http://dx.doi.org/10.1186/s12935-019-0964-1

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