Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization

BACKGROUND: Medulloblastoma (MB), the most common pediatric brain cancer, presents with a poor prognosis in a subset of patients with high risk disease, or at recurrence, where current therapies are ineffective. Cord blood (CB) natural killer (NK) cells may be promising off-the-shelf effector cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Powell, Allison B., Yadavilli, Sridevi, Saunders, Devin, Van Pelt, Stacey, Chorvinsky, Elizabeth, Burga, Rachel A., Albihani, Shuroug, Hanley, Patrick J., Xu, Zhenhua, Pei, Yanxin, Yvon, Eric S., Hwang, Eugene I., Bollard, Catherine M., Nazarian, Javad, Cruz, Conrad Russell Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757414/
https://www.ncbi.nlm.nih.gov/pubmed/31547819
http://dx.doi.org/10.1186/s12967-019-2055-4

Ejemplares similares

Ejemplares similares