Altered Toll-Like Receptor Signalling in Children with Down Syndrome

Toll-like receptors (TLRs) are the key in initiating innate immune responses. TLR2 is crucial in recognising lipopeptides from gram-positive bacteria and is implicated in chronic inflammation. Children with Down syndrome (DS) are prone to infections from these pathogens and have an increased risk of...

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Detalles Bibliográficos
Autores principales: Huggard, Dean, Koay, W. J., Kelly, Lynne, McGrane, Fiona, Ryan, Emer, Lagan, Niamh, Roche, Edna, Balfe, Joanne, Leahy, T. Ronan, Franklin, Orla, Moreno-Oliveira, Ana, Melo, Ashanty M., Doherty, Derek G., Molloy, Eleanor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757445/
https://www.ncbi.nlm.nih.gov/pubmed/31611734
http://dx.doi.org/10.1155/2019/4068734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757445/
https://www.ncbi.nlm.nih.gov/pubmed/31611734
http://dx.doi.org/10.1155/2019/4068734

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