Altered Toll-Like Receptor Signalling in Children with Down Syndrome

Toll-like receptors (TLRs) are the key in initiating innate immune responses. TLR2 is crucial in recognising lipopeptides from gram-positive bacteria and is implicated in chronic inflammation. Children with Down syndrome (DS) are prone to infections from these pathogens and have an increased risk of...

Descripción completa

Detalles Bibliográficos
Autores principales: Huggard, Dean, Koay, W. J., Kelly, Lynne, McGrane, Fiona, Ryan, Emer, Lagan, Niamh, Roche, Edna, Balfe, Joanne, Leahy, T. Ronan, Franklin, Orla, Moreno-Oliveira, Ana, Melo, Ashanty M., Doherty, Derek G., Molloy, Eleanor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757445/
https://www.ncbi.nlm.nih.gov/pubmed/31611734
http://dx.doi.org/10.1155/2019/4068734

Ejemplares similares

Ejemplares similares