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Portable all-fiber dual-output widely tunable light source for coherent Raman imaging
We present a rapidly tunable dual-output all-fiber light source for coherent Raman imaging, based on a dispersively matched mode-locked laser pumping a parametric oscillator. Output pump and Stokes pulses with a maximal power of 170 and 400 mW, respectively, and equal durations of 7 ps could be gene...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757451/ https://www.ncbi.nlm.nih.gov/pubmed/31565500 http://dx.doi.org/10.1364/BOE.10.004437 |
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author | Brinkmann, Maximilian Fast, Alexander Hellwig, Tim Pence, Isaac Evans, Conor L. Fallnich, Carsten |
author_facet | Brinkmann, Maximilian Fast, Alexander Hellwig, Tim Pence, Isaac Evans, Conor L. Fallnich, Carsten |
author_sort | Brinkmann, Maximilian |
collection | PubMed |
description | We present a rapidly tunable dual-output all-fiber light source for coherent Raman imaging, based on a dispersively matched mode-locked laser pumping a parametric oscillator. Output pump and Stokes pulses with a maximal power of 170 and 400 mW, respectively, and equal durations of 7 ps could be generated. The tuning mechanism required no mechanical delay line, enabling all-electronic arbitrary wavelength switching across more than 2700 [Formula: see text] in less than 5 ms. The compact setup showed a reliable operation despite mechanical shocks of more than 25 [Formula: see text] and is, thus, well suited for operation in a mobile cart. Imaging mouse and human skin tissue with both the portable light source and a commercial laboratory-bound reference system yielded qualitatively equal results and verified the portable light source being well suited for coherent Raman microscopy. |
format | Online Article Text |
id | pubmed-6757451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-67574512019-09-27 Portable all-fiber dual-output widely tunable light source for coherent Raman imaging Brinkmann, Maximilian Fast, Alexander Hellwig, Tim Pence, Isaac Evans, Conor L. Fallnich, Carsten Biomed Opt Express Article We present a rapidly tunable dual-output all-fiber light source for coherent Raman imaging, based on a dispersively matched mode-locked laser pumping a parametric oscillator. Output pump and Stokes pulses with a maximal power of 170 and 400 mW, respectively, and equal durations of 7 ps could be generated. The tuning mechanism required no mechanical delay line, enabling all-electronic arbitrary wavelength switching across more than 2700 [Formula: see text] in less than 5 ms. The compact setup showed a reliable operation despite mechanical shocks of more than 25 [Formula: see text] and is, thus, well suited for operation in a mobile cart. Imaging mouse and human skin tissue with both the portable light source and a commercial laboratory-bound reference system yielded qualitatively equal results and verified the portable light source being well suited for coherent Raman microscopy. Optical Society of America 2019-08-05 /pmc/articles/PMC6757451/ /pubmed/31565500 http://dx.doi.org/10.1364/BOE.10.004437 Text en Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) . Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. |
spellingShingle | Article Brinkmann, Maximilian Fast, Alexander Hellwig, Tim Pence, Isaac Evans, Conor L. Fallnich, Carsten Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title | Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title_full | Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title_fullStr | Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title_full_unstemmed | Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title_short | Portable all-fiber dual-output widely tunable light source for coherent Raman imaging |
title_sort | portable all-fiber dual-output widely tunable light source for coherent raman imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757451/ https://www.ncbi.nlm.nih.gov/pubmed/31565500 http://dx.doi.org/10.1364/BOE.10.004437 |
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