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Piper sarmentosum Promotes Endothelial Nitric Oxide Production by Reducing Asymmetric Dimethylarginine in Tumor Necrosis Factor-α-Induced Human Umbilical Vein Endothelial Cells

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase (eNOS). ADMA is degraded by dimethylarginine dimethylaminohydrolase (DDAH). Elevated levels of ADMA lead to reduction in nitric oxide (NO) production, which is linked to endothelial dysfunction and ath...

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Detalles Bibliográficos
Autores principales:	Sundar, Uma Mahgesswary, Ugusman, Azizah, Chua, Hui Kien, Latip, Jalifah, Aminuddin, Amilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758593/ https://www.ncbi.nlm.nih.gov/pubmed/31607906 http://dx.doi.org/10.3389/fphar.2019.01033

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