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The Presence of a CMV Immunodominant Allele in the Recipient Is Associated With Increased Survival in CMV Positive Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation

Specific major histocompatibility (MHC) class I alleles dominate anti-CMV responses in a hierarchal manner. These CMV immunodominant (IMD) alleles are associated with a higher magnitude and frequency of cytotoxic lymphocyte responses as compared to other human leukocyte antigen (HLA) alleles. CMV re...

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Detalles Bibliográficos
Autores principales: Grosso, Dolores, Leiby, Benjamin, Carabasi, Matthew, Filicko-O'Hara, Joanne, Gaballa, Sameh, O'Hara, William, Wagner, John L., Flomenberg, Neal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758597/
https://www.ncbi.nlm.nih.gov/pubmed/31608225
http://dx.doi.org/10.3389/fonc.2019.00888