(1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses

AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress such as salt stress. Snf1 regulates metabolic enzymes such as acetyl-CoA carb...

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Detalles Bibliográficos
Autores principales: Kim, Jiyoung, Oh, Junsang, Yoon, Deok-Hyo, Sung, Gi-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758625/
https://www.ncbi.nlm.nih.gov/pubmed/31565471
http://dx.doi.org/10.1080/12298093.2019.1625854
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author Kim, Jiyoung
Oh, Junsang
Yoon, Deok-Hyo
Sung, Gi-Ho
author_facet Kim, Jiyoung
Oh, Junsang
Yoon, Deok-Hyo
Sung, Gi-Ho
author_sort Kim, Jiyoung
collection PubMed
description AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress such as salt stress. Snf1 regulates metabolic enzymes such as acetyl-CoA carboxylase, indicating a possible role for Snf1 in metabolic regulation. In this article, we performed nuclear magnetic resonance (NMR) spectroscopy to profile the metabolic changes induced by Snf1 under environmental stress. According to our NMR data, we suggest that Snf1 plays a role in regulating cellular concentrations of a variety of metabolites during environmental stress responses.
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spelling pubmed-67586252019-09-27 (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses Kim, Jiyoung Oh, Junsang Yoon, Deok-Hyo Sung, Gi-Ho Mycobiology Research Note AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress such as salt stress. Snf1 regulates metabolic enzymes such as acetyl-CoA carboxylase, indicating a possible role for Snf1 in metabolic regulation. In this article, we performed nuclear magnetic resonance (NMR) spectroscopy to profile the metabolic changes induced by Snf1 under environmental stress. According to our NMR data, we suggest that Snf1 plays a role in regulating cellular concentrations of a variety of metabolites during environmental stress responses. Taylor & Francis 2019-07-01 /pmc/articles/PMC6758625/ /pubmed/31565471 http://dx.doi.org/10.1080/12298093.2019.1625854 Text en © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of the Korean Society of Mycology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Note
Kim, Jiyoung
Oh, Junsang
Yoon, Deok-Hyo
Sung, Gi-Ho
(1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title_full (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title_fullStr (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title_full_unstemmed (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title_short (1)H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
title_sort (1)h-nmr analysis of metabolic changes induced by snf1/amp-activated protein kinase during environmental stress responses
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758625/
https://www.ncbi.nlm.nih.gov/pubmed/31565471
http://dx.doi.org/10.1080/12298093.2019.1625854
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