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Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner

Background: Tissue factor (TF) combined with its ligand FVII initiates blood coagulation and intracellular signaling. Obese and type 2 diabetic subjects have increased TF expression in their adipose tissue and an increased risk for thrombotic complications. Here we address the role of TF/FVII on adi...

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Detalles Bibliográficos
Autores principales: Edén, Desirée, Panagiotou, Grigorios, Mokhtari, Dariush, Eriksson, Jan W., Åberg, Mikael, Siegbahn, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758637/
https://www.ncbi.nlm.nih.gov/pubmed/31407948
http://dx.doi.org/10.1080/03009734.2019.1645248