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Autoactivation of small GTPases by the GEF–effector positive feedback modules

Small GTPases are organizers of a plethora of cellular processes. The time and place of their activation are tightly controlled by the localization and activation of their regulators, guanine-nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Remarkably, in some systems, the u...

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Detalles Bibliográficos
Autores principales: Goryachev, Andrew B., Leda, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758843/
https://www.ncbi.nlm.nih.gov/pubmed/31583084
http://dx.doi.org/10.12688/f1000research.20003.1