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Autoactivation of small GTPases by the GEF–effector positive feedback modules
Small GTPases are organizers of a plethora of cellular processes. The time and place of their activation are tightly controlled by the localization and activation of their regulators, guanine-nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Remarkably, in some systems, the u...
Autores principales: | Goryachev, Andrew B., Leda, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758843/ https://www.ncbi.nlm.nih.gov/pubmed/31583084 http://dx.doi.org/10.12688/f1000research.20003.1 |
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