Migratory Polyarthritis in the Setting of Chlamydial Infection

Reactive arthritis is defined as a sterile inflammation involving the synovial membrane, tendons and/or fascia, elicited by an infection, usually originating from gastrointestinal or genitourinary tracts. Reactive arthritis can also be triggered by a sexually transmitted disease, referred to as sexually acquired reactive arthritis. The most common identifiable cause of non-gonococcal urethritis is Chlamydia trachomatis. Herein, we present a case of a 30-year-old healthy male patient, who developed migratory oligoarthritis in the setting of elevated inflammatory markers, highlighting the importance of obtaining an appropriate history and ordering pertinent laboratory tests, along with literature review on reactive arthritis.