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Molecular Testing Identifies Determinants of Exceptional Response and Guides Precision Therapy in a Patient with Lethal, Treatment-emergent Neuroendocrine Prostate Cancer

Nearly all prostate cancers start out as adenocarcinomas driven by the androgen receptor (AR). Neuroendocrine prostate cancer (NEPC) is a rare, AR-independent subtype with a poor prognosis and limited treatment options. Importantly, because of the widespread use of novel AR-targeting agents, the inc...

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Detalles Bibliográficos
Autores principales:	Turina, Claire B, Coleman, Daniel J, Thomas, George V, Fung, Alice W, Alumkal, Joshi J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758987/ https://www.ncbi.nlm.nih.gov/pubmed/31565603 http://dx.doi.org/10.7759/cureus.5197

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