Cargando…
Anti-N-methyl-D-aspartate Receptor Encephalitis
Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and n...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759002/ https://www.ncbi.nlm.nih.gov/pubmed/31565599 http://dx.doi.org/10.7759/cureus.5192 |
_version_ | 1783453623632527360 |
---|---|
author | Tanquary, Gregory Fraser, William Bowers, Kaitlin M |
author_facet | Tanquary, Gregory Fraser, William Bowers, Kaitlin M |
author_sort | Tanquary, Gregory |
collection | PubMed |
description | Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities. It is commonly associated with ovarian teratoma. Our case illustrates anti-NMDA encephalitis presenting in a young female with progressive mental status changes and neurologic abnormalities throughout her emergency department course. We review the investigative approach, diagnostic modalities, and treatment options in patient management. This case emphasizes the need for a high index of suspicion of anti-NMDA receptor encephalitis when approaching a patient with unexplained changes in mentation. |
format | Online Article Text |
id | pubmed-6759002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-67590022019-09-28 Anti-N-methyl-D-aspartate Receptor Encephalitis Tanquary, Gregory Fraser, William Bowers, Kaitlin M Cureus Emergency Medicine Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities. It is commonly associated with ovarian teratoma. Our case illustrates anti-NMDA encephalitis presenting in a young female with progressive mental status changes and neurologic abnormalities throughout her emergency department course. We review the investigative approach, diagnostic modalities, and treatment options in patient management. This case emphasizes the need for a high index of suspicion of anti-NMDA receptor encephalitis when approaching a patient with unexplained changes in mentation. Cureus 2019-07-22 /pmc/articles/PMC6759002/ /pubmed/31565599 http://dx.doi.org/10.7759/cureus.5192 Text en Copyright © 2019, Tanquary et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Emergency Medicine Tanquary, Gregory Fraser, William Bowers, Kaitlin M Anti-N-methyl-D-aspartate Receptor Encephalitis |
title | Anti-N-methyl-D-aspartate Receptor Encephalitis |
title_full | Anti-N-methyl-D-aspartate Receptor Encephalitis |
title_fullStr | Anti-N-methyl-D-aspartate Receptor Encephalitis |
title_full_unstemmed | Anti-N-methyl-D-aspartate Receptor Encephalitis |
title_short | Anti-N-methyl-D-aspartate Receptor Encephalitis |
title_sort | anti-n-methyl-d-aspartate receptor encephalitis |
topic | Emergency Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759002/ https://www.ncbi.nlm.nih.gov/pubmed/31565599 http://dx.doi.org/10.7759/cureus.5192 |
work_keys_str_mv | AT tanquarygregory antinmethyldaspartatereceptorencephalitis AT fraserwilliam antinmethyldaspartatereceptorencephalitis AT bowerskaitlinm antinmethyldaspartatereceptorencephalitis |