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Metformin improved oxidized low-density lipoprotein-impaired mitochondrial function and increased glucose uptake involving Akt-AS160 pathway in raw264.7 macrophages

BACKGROUND: Macrophage accumulation in the vascular wall is a hallmark of atherosclerosis. Studies showed that shifting of oxidized lipids-induced inflammatory macrophages towards an anti-inflammatory phenotype by promoting oxidative metabolism attenuated atherosclerosis progression. Therefore, this...

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Detalles Bibliográficos
Autores principales:	He, Xuan, Wang, Lei, Chen, Xiu-Fang, Liang, Qiao, Wang, Wen-Qing, Lin, An-Qi, Yi, Long, Wang, Yong, Gao, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759109/ https://www.ncbi.nlm.nih.gov/pubmed/31268904 http://dx.doi.org/10.1097/CM9.0000000000000333

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