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A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats

A fatty acid analogue, 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), was previously shown to have hypolipidemic effects in rats by targeting mitochondrial activity predominantly in liver. This study aimed to determine if 1-triple TTA could influence carbohydrate metabolism. Male Wistar rats w...

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Detalles Bibliográficos
Autores principales: Lindquist, Carine, Bjørndal, Bodil, Bakke, Hege G., Slettom, Grete, Karoliussen, Marie, Rustan, Arild C., Thoresen, G. Hege, Skorve, Jon, Nygård, Ottar K., Berge, Rolf Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759202/
https://www.ncbi.nlm.nih.gov/pubmed/31550253
http://dx.doi.org/10.1371/journal.pone.0222558