Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir

Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2–98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have...

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Autores principales: Mishin, Vasiliy P., Patel, Mira C., Chesnokov, Anton, De La Cruz, Juan, Nguyen, Ha T., Lollis, Lori, Hodges, Erin, Jang, Yunho, Barnes, John, Uyeki, Timothy, Davis, Charles T., Wentworth, David E., Gubareva, Larisa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759234/
https://www.ncbi.nlm.nih.gov/pubmed/31287050
http://dx.doi.org/10.3201/eid2510.190607
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author Mishin, Vasiliy P.
Patel, Mira C.
Chesnokov, Anton
De La Cruz, Juan
Nguyen, Ha T.
Lollis, Lori
Hodges, Erin
Jang, Yunho
Barnes, John
Uyeki, Timothy
Davis, Charles T.
Wentworth, David E.
Gubareva, Larisa V.
author_facet Mishin, Vasiliy P.
Patel, Mira C.
Chesnokov, Anton
De La Cruz, Juan
Nguyen, Ha T.
Lollis, Lori
Hodges, Erin
Jang, Yunho
Barnes, John
Uyeki, Timothy
Davis, Charles T.
Wentworth, David E.
Gubareva, Larisa V.
author_sort Mishin, Vasiliy P.
collection PubMed
description Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2–98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.
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spelling pubmed-67592342019-10-02 Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir Mishin, Vasiliy P. Patel, Mira C. Chesnokov, Anton De La Cruz, Juan Nguyen, Ha T. Lollis, Lori Hodges, Erin Jang, Yunho Barnes, John Uyeki, Timothy Davis, Charles T. Wentworth, David E. Gubareva, Larisa V. Emerg Infect Dis Dispatch Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2–98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors. Centers for Disease Control and Prevention 2019-10 /pmc/articles/PMC6759234/ /pubmed/31287050 http://dx.doi.org/10.3201/eid2510.190607 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Mishin, Vasiliy P.
Patel, Mira C.
Chesnokov, Anton
De La Cruz, Juan
Nguyen, Ha T.
Lollis, Lori
Hodges, Erin
Jang, Yunho
Barnes, John
Uyeki, Timothy
Davis, Charles T.
Wentworth, David E.
Gubareva, Larisa V.
Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title_full Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title_fullStr Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title_full_unstemmed Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title_short Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir
title_sort susceptibility of influenza a, b, c, and d viruses to baloxavir
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759234/
https://www.ncbi.nlm.nih.gov/pubmed/31287050
http://dx.doi.org/10.3201/eid2510.190607
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