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Control and Elimination of Extensively Drug-Resistant Acinetobacter baumanii in an Intensive Care Unit

We decreased antimicrobial drug consumption in an intensive care unit in Lebanon by changing to colistin monotherapy for extensively drug-resistant Acinetobacter baumanii infections. We saw a 78% decrease of A. baumanii in sputum and near-elimination of bla(oxa-23)-carrying sequence type 2 clone ove...

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Detalles Bibliográficos
Autores principales: Chamieh, Amanda, Nawfal, Tania Dagher, Ballouz, Tala, Afif, Claude, Juvelekian, George, Hlais, Sani, Rolain, Jean-Marc, Azar, Eid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759246/
https://www.ncbi.nlm.nih.gov/pubmed/31538925
http://dx.doi.org/10.3201/eid2510.181626
Descripción
Sumario:We decreased antimicrobial drug consumption in an intensive care unit in Lebanon by changing to colistin monotherapy for extensively drug-resistant Acinetobacter baumanii infections. We saw a 78% decrease of A. baumanii in sputum and near-elimination of bla(oxa-23)-carrying sequence type 2 clone over the 1-year study. Non–A. baumanii multidrug-resistant infections remained stable.