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Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018

We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017–2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolat...

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Autores principales: Pohlmann, Anne, Hoffmann, Donata, Grund, Christian, Koethe, Susanne, Hüssy, Daniela, Meier, Simone M., King, Jacqueline, Schinköthe, Jan, Ulrich, Reiner, Harder, Timm, Beer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759249/
https://www.ncbi.nlm.nih.gov/pubmed/31538926
http://dx.doi.org/10.3201/eid2510.181931
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author Pohlmann, Anne
Hoffmann, Donata
Grund, Christian
Koethe, Susanne
Hüssy, Daniela
Meier, Simone M.
King, Jacqueline
Schinköthe, Jan
Ulrich, Reiner
Harder, Timm
Beer, Martin
author_facet Pohlmann, Anne
Hoffmann, Donata
Grund, Christian
Koethe, Susanne
Hüssy, Daniela
Meier, Simone M.
King, Jacqueline
Schinköthe, Jan
Ulrich, Reiner
Harder, Timm
Beer, Martin
author_sort Pohlmann, Anne
collection PubMed
description We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017–2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.
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spelling pubmed-67592492019-10-02 Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018 Pohlmann, Anne Hoffmann, Donata Grund, Christian Koethe, Susanne Hüssy, Daniela Meier, Simone M. King, Jacqueline Schinköthe, Jan Ulrich, Reiner Harder, Timm Beer, Martin Emerg Infect Dis Dispatch We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017–2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment. Centers for Disease Control and Prevention 2019-10 /pmc/articles/PMC6759249/ /pubmed/31538926 http://dx.doi.org/10.3201/eid2510.181931 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Pohlmann, Anne
Hoffmann, Donata
Grund, Christian
Koethe, Susanne
Hüssy, Daniela
Meier, Simone M.
King, Jacqueline
Schinköthe, Jan
Ulrich, Reiner
Harder, Timm
Beer, Martin
Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title_full Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title_fullStr Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title_full_unstemmed Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title_short Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018
title_sort genetic characterization and zoonotic potential of highly pathogenic avian influenza virus a(h5n6/h5n5), germany, 2017–2018
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759249/
https://www.ncbi.nlm.nih.gov/pubmed/31538926
http://dx.doi.org/10.3201/eid2510.181931
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