Cargando…
Calpains of Leishmania braziliensis: genome analysis, differential expression, and functional analysis
BACKGROUND: Calpains are proteins belonging to the multi-gene family of calcium-dependent cysteine peptidases that undergo tight on/off regulation, and uncontrolled proteolysis of calpains is associated with severe human pathologies. Calpain orthologues are expanded and diversified in the trypanosom...
Autores principales: | Ennes-Vidal, Vítor, Vitório, Bianca da Silva, Menna-Barreto, Rubem Figueiredo Sadok, Pitaluga, André Nóbrega, Gonçalves-da-Silva, Silvia Amaral, Branquinha, Marta Helena, Santos, André Luis Souza, d’Avila-Levy, Claudia Masini |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759280/ https://www.ncbi.nlm.nih.gov/pubmed/31553371 http://dx.doi.org/10.1590/0074-02760190147 |
Ejemplares similares
-
Expression and cellular localisation of Trypanosoma cruzi calpains
por: Ennes-Vidal, Vítor, et al.
Publicado: (2020) -
Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis?
por: ENNES-VIDAL, VITOR, et al.
Publicado: (2017) -
MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut
por: Ennes-Vidal, Vítor, et al.
Publicado: (2011) -
The Diverse Calpain Family in Trypanosomatidae: Functional Proteins Devoid of Proteolytic Activity?
por: Ennes-Vidal, Vítor, et al.
Publicado: (2021) -
Proteolytic inhibitors as alternative medicines to treat trypanosomatid-caused diseases: experience with calpain inhibitors
por: Ennes-Vidal, Vítor, et al.
Publicado: (2022)